Choose what you want to give a f*ck about.
Being comfortable with being different doesn't mean being indifferent. Indifferent people do not give a f*ck about anything. Those who are comfortable with being different, separate the important from the unimportant, and only give a f*ck about what’s important.
Additionally, being comfortable with being different means not giving up in the face of adversity and being confident in your abilities to achieve your goals.
Keep in mind that sometimes, you may try your hardest but still fail. Even if you do not get the results you were aiming for, as long as you truly tried your best, you will be much happier than if you hadn’t at all.